News

Posted on May 19, 2018

The Cause And Future Of Physician Burnout: Abraham Verghese

The biggest price for “digital medicine” is being paid by physicians like the sad case seated before me, who is already considering jumping to venture capital or a start-up, not because that is where the heart is but because it’s a place to bail out to. By some estimates, more than 50 percent of physicians […] Read More

Posted on May 16, 2018

Micro-RNA Is An Important And Repairable Target For Cancer Prevention: Raymond Rupert MD, MBA.

Micro RNA Is An Important And Repairable Target For Cancer Prevention: Raymond Rupert MD, MBA.  www.rupertcasemanagement.com In epigenetics, micro RNA can turn genes on and off. If a tumour suppressor gene is turned off by micro RNA, then cancer might develop. It is only now that doctors are recognizing how important micro RNA is in […] Read More

Posted on May 9, 2018

RNA Takes A Central Role In Cancer: Raymond Rupert MD, MBA.

RNA Takes A Central Role in Cancer:  Recent studies have shown that depressed patients have alternations in their RNA.  The changes are presumed to be the result of mental, cognitive and medicinal treatments. The RNA serves as a messenger and determines which components of our DNA will be expressed and which proteins our body will […] Read More

Posted on May 3, 2018

Francis Collins NIH Director On Gene Editing: Stat News

I’m very excited about the potential of gene-editing to cure rare diseases for which we know the molecular defect and there’s no current therapy. CRISPR-Cas9 has made it possible not just to dream about such protocols, but actually design them. I think this will be the year where we will see the first clinical trials […] Read More

Posted on April 28, 2018

Did Betsy Get Value From Her Lawyer? Raymond Rupert MD, MBA.

Betsy is 61 years of age. She works as an editor in Calgary. She is in the midst of a divorce with her high earner husband. In fact, he earns over $1,00,000 per year. He is an odd duck. When he moved out of the matrimonial house, he had 126 brand new shirts which had […] Read More

Posted on April 25, 2018

We Found This Fact About Operating Room Availability Very Interesting. Raymond Rupert MD, MBA.

Recently, we spoke to a liver transplant surgeon at the Mayo Clinic. He has worked there for about one year. He used to work at the Toronto General Hospital. He is a gifted surgeon. He can tackle just about any degree of surgical complexity. Because of that, he was recruited to work at the Mayo. […] Read More

Posted on April 23, 2018

New Ultrasound Technology for Prostate Cancer:

Scientists have announced the development of a highly accurate and reliable technique for diagnosing prostate cancer. The Dundee University-based team say they have used an ultrasound process called shear wave elastography (SWE) to detect prostate tumours. The method is non-invasive and cheaper than current detection techniques. … The new method aims to get round the […] Read More

Posted on April 21, 2018

National Pharmacare Is Pending: Raymond Rupert MD, MBA.

National Pharmacare Is Pending: Let’s Think About  Maximizing Access For All Canadians  Raymond Rupert MD, MBA. The House of Commons’ standing committee on health is recommending the creation of a universal, single public payer prescription drug coverage program for all Canadians. “The committee believes that the best approach for the creation of such a program […] Read More

Posted on April 19, 2018

Dropping Big Data To Focus On Small Data: Raymond Rupert MD, MBA.

  Dropping Big Data To Focus On Small Data At Rupert Case Management:  Raymond Rupert MD, MBA. The world is obsessed with big data.  Data collected from many persons.  We are pleased to be contrarians. We focus on small data collected from one person. Small data is the really important data that makes all the […] Read More

Posted on April 13, 2018

A Computer Greeted My Patient In The Emergency Department: Story As Told By A Patient

A Computer Greeted My Patient In The Emergency Department: A Story As Told By A Patient  The patient reluctantly had to go to the ER for an infection of his nose. It was painful. It was not going to go away.  His family encouraged him to go to the ER. When he got there, he […] Read More

Posted on April 12, 2018

Immunotherapy and Melanoma: Does it work or not work? Raymond Rupert MD, MBA

How melanoma evades the immune system the secret is the macrophages in the tumour which block the immunotherapy drugs… read on. Scientists have pinpointed a pathway that helps melanoma evade the immune system’s attacks — and in turn, have found a a potential reason why the cancer cells doesn’t always respond to certain drugs. Here’s what […] Read More

Posted on April 12, 2018

Targeted EEG Measurements To Predict Treatment Outcomes In Depression:

Key Points Of The Study: Question  Does increased pretreatment rostral anterior cingulate cortex theta activity have incremental predictive validity with respect to treatment outcome in major depression? Findings  In a randomized clinical trial including 296 patients with major depressive disorder, higher rostral anterior cingulate cortex theta activity at both baseline and week 1 predicted greater improvement in […] Read More

Posted on April 12, 2018

Phage Therapy When Antibiotics Fail To Help…. Raymond Rupert MD, MBA.

A case study of phage treatment where antibiotics had failed.  A phage is a virus that attacks bacteria and can kill them. Very important when antibiotics are not working because of resistance. The bacteria have learned to evade the antibiotics. In 2015, Thomas Patterson, a professor at the University of California, San Diego, was on holiday […] Read More

Posted on April 11, 2018

Informed Consent In Mental Health- Stephanie McMahon and Virgil Stucker

Informed Consent In Mental Health Care April 10, 2018 | Stephanie McMahon The term “informed consent” is used a lot in mental health care. Those two little words are a big, and complicated, deal.  In this blog post, I unpack the term “informed consent” and all the things that come along with it: dignity of risk, […] Read More

Posted on April 11, 2018

Challenges With Capacity: Raymond Rupert MD, MBA.

Dr. Raymond Rupert, MD, MBA of Rupert Case Management in Toronto, Ontario comments on the difficulty around assessing capacity: “When an individual is clearly at risk of harming themselves or another and appears out of control, then the decision about capacity is relatively easy. And the legal and other processes work well. However, when the individual appears to be […] Read More

Posted on March 28, 2018

Confusion Diagnosing Mitochondrial Disease: Neurology Genetics April 01, 2018; 4 (2)

Confusion Diagnosing Mitochondrial Disease: Source: Neurology Genetics April 01, 2018; 4 (2)  The results highlight the difficulty, confusion, and burden that individuals with suspected mitochondrial disease typically undergo in obtaining a diagnosis. While the survey failed to capture the amount of time that typically elapses between the symptom onset and diagnosis, it is clear from several […] Read More

Posted on March 26, 2018

22 Years And A Solid Evidence Based Treatment For Stroke Is Still Not Accepted: New York Times March 26 2018

It was one of those findings that would change medicine, Dr. Christopher Lewandowski thought. For years, doctors had tried — and failed — to find a treatment that would preserve the brains of stroke patients. The task was beginning to seem hopeless: Once a clot blocked a blood vessel supplying the brain, its cells quickly […] Read More

Posted on March 26, 2018

Forecast For Increasing Catastrophic Drug Costs In Ontario:

There are almost 130,000 Ontario residents who have catastrophic drug expenses and need government assistance to cover their costly medications, a new study shows. The research, published in the medical journal CMAJ Open, shows that both the numbers of users and the overall cost of the Trillium Drug Program are soaring. Researchers examined claims to […] Read More

Posted on March 26, 2018

Computational Analysis And Intelligent Computing Systems To Assist Oncologists With Personalized Cancer Treatments:

RCM Provides Advanced Computational Analysis to Assist Oncologists in Delivering Personalized Cancer Treatments based on Genetic Markers   The research is clear:  Genetic markers of cancer, which are identified through an analysis of cancer DNA in a lab, can help oncologists personalize treatments for improved outcomes and prolonged survival rates.   Here’s how it works:  Oncologist receive […] Read More

Posted on February 17, 2018

Mixing Mathematics And Medicine Leads To Surgical Innovation:

 Dr. Eitan Prisman is a head and neck surgeon with a background in mathematics. He has mixed these disciplines and reinvented the wheel for complex head and neck patients. With funding from the Vancouver Coastal Health Research Institute, Dr. Prisman and his team have developed their own made-in-Vancouver 3D simulation software that’s already improving surgery […] Read More

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